Prognostic evaluation models for primary thyroid lymphoma, based on the SEER database and an external validation cohort.

ABSTRACT:

Purpose

Primary thyroid lymphoma (PTL) is a rare malignancy, and the literature is limited to small case series and case reports. This study aimed to assess the epidemiologic characteristics, survival, and prognostic factors of patients with PTL.

Methods

We analyzed 2215 PTL patients from the Surveillance, Epidemiology, and End Results database medical records, between 1983 and 2015, as the training cohort. We enrolled 105 patients from the Cancer Hospital, Chinese Academy of Medical Sciences, for the external validation cohort. The nomograms for predicting the 1-, 5-, and 10-year overall survival (OS) and lymphoma-specific survival (LSS) were constructed.

Results

PTL incidence steadily increased from 1977 to 1994, with an annual percentage change of 3.2% (95% confide

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC8918170 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature