Risk of conversion from mild cognitive impairment to dementia in low- and middle-income countries: A systematic review and meta-analysis.

ABSTRACT:

Introduction

With no treatment for dementia, there is a need to identify high risk cases to focus preventive strategies, particularly in low- and middle-income countries (LMICs) where the burden of dementia is greatest. We evaluated the risk of conversion from mild cognitive ompairment (MCI) to dementia in LMICs.

Methods

Medline, Embase, PsycINFO, and Scopus were searched from inception until June 30, 2020. The search was restricted to observational studies, conducted in population-based samples, with at least 1 year follow-up. There was no restriction on the definition of MCI used as long as it was clearly defined. PROSPERO registration: CRD42019130958.

Results

Ten thousand six hundred forty-seven articles were screened; n = 11 retained. Of the 11 studies, mos

SUBMITTER: McGrattan AM 

PROVIDER: S-EPMC8918697 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature