Serum lactate levels in cirrhosis and non-cirrhosis patients with septic shock.

ABSTRACT:

Background

In septic shock patients with cirrhosis, impaired liver function might decrease lactate elimination and produce a higher lactate level. This study investigated differences in initial lactate, lactate clearance, and lactate utility between cirrhotic and non-cirrhotic septic shock patients.

Methods

This is a retrospective cohort study conducted at a referral, university-affiliated medical center. We enrolled adults admitted during 2012-2018 who satisfied the septic shock diagnostic criteria of the Surviving Sepsis Campaign: 2012. Patients previously diagnosed with cirrhosis by an imaging modality were classified into the cirrhosis group. The initial lactate levels and levels 6 hours after resuscitation were measured and used to calculate lactate clearance. We compar

SUBMITTER: Tongyoo S 

PROVIDER: S-EPMC8918713 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature