Association of Lean Body Mass and Fat Mass With 1-Year Mortality Among Patients With Heart Failure.

ABSTRACT:

Background

Prior studies have found an unexplained inverse or U-shaped relationship between body mass index (BMI) and mortality in heart failure (HF) patients. However, little is known about the independent effects of each body component, i.e., lean body mass (LBM) and fat mass (FM), on mortality.

Methods

We used data from the China Patient-centered Evaluative Assessment of Cardiac Events-Prospective Heart Failure Study. LBM and FM were calculated using equations developed from the National Health and Nutrition Examination Survey. LBM and FM index, calculated by dividing LBM or FM in kilograms by the square of height in meters, were used for analysis. We used restricted cubic spline and Cox model to examine the association of LBM and FM index with 1-year all-cause mortality.

SUBMITTER: Ge Y 

PROVIDER: S-EPMC8918916 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature