Membrane Phase Drives the Assembly of Gold Nanoparticles on Biomimetic Lipid Bilayers.

ABSTRACT: In recent years, many efforts have been devoted to investigating the interaction of nanoparticles (NPs) with lipid biomimetic interfaces, both from a fundamental perspective aimed at understanding relevant phenomena occurring at the nanobio interface and from an application standpoint for the design of novel lipid-nanoparticle hybrid materials. In this area, recent reports have revealed that citrate-capped gold nanoparticles (AuNPs) spontaneously associate with synthetic phospholipid liposomes and, in some cases, self-assemble on the lipid bilayer. However, the mechanistic and kinetic aspects of this phenomenon are not yet completely understood. In this study, we address the kinetics of interaction of citrate-capped AuNP with lipid vesicles of different rigidities (gel-phase rigid membrane

SUBMITTER: Cardellini J 

PROVIDER: S-EPMC8919252 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature