Clinical trials targeting neurofibromatoses-associated tumors: a systematic review.

ABSTRACT:

Background

There is a paucity of literature that comprehensively analyzes previous and current clinical trials targeting neurofibromatoses-related tumors. This article aims to provide readers with drug development efforts targeting these tumors by analyzing translational and clinical findings.

Methods

This systematic review was written according to the PRISMA guidelines. Inclusion criteria were clinical trials involving patients with neurofibromatosis type 1, type 2, or schwannomatosis that were treated with therapies targeting neurofibromatoses-associated tumors and that were registered on clinicaltrials.gov. In addition, a search was performed in PubMed, Web of Science, Google Scholar, and Embase European for articles fully describing these clinical trials.

Results

SUBMITTER: Roman Souza G 

PROVIDER: S-EPMC8919406 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature