Adverse effects of cell-free and concentrated ascites reinfusion therapy for malignant ascites: a single-institute experience.

ABSTRACT:

Background

Cell-free and concentrated ascites reinfusion therapy (CART) is a strategy for improving various intractable symptoms due to refractory ascites, including hypoalbuminemia. CART has recently been applied in the treatment of cancer patients. This study was performed to assess the safety of CART in a single cancer institute.

Methods

We retrospectively reviewed 233 CART procedures that were performed for 132 cancer patients in our institute.

Results

The median weight of ascites before and after concentration was 4,720 g and 490 g (median concentration rate, 10.0-fold), The median amounts of total protein and albumin were 64.0 g and 32.6 g (median recovery rates, 44.9% and 49.0%), respectively. Thirty-three adverse events (AEs) were observed in 22 (9.4%) of 233

SUBMITTER: Tsubokura M 

PROVIDER: S-EPMC8919605 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature