Ontology highlight
ABSTRACT: Background
Skin sensation is the primary factor limiting the intensity of transcranial electrical stimulation (tES). It is well established that different waveforms generate different sensations, yet transcranial stimulation has been limited to a relatively small number of prototypical waveforms.Objective
We explore whether alternative stimulation waveforms could substantially reduce skin sensation and thus allow for stronger intensities in tES.Methods
We systematically tested a range of waveforms in a series of 6 exploratory experiments stimulating human adults on the forearm and in one instance on the head. Subjects were asked to rate skin sensation level on a numerical scale from "none" to "extreme".Results
High frequency (>1 kHz) monophasic square wave s
SUBMITTER: Hsu G
PROVIDER: S-EPMC8919780 | biostudies-literature | 2021 May-Jun
REPOSITORIES: biostudies-literature