Acids produced by lactobacilli inhibit the growth of commensal Lachnospiraceae and S24-7 bacteria.

ABSTRACT: The Lactobacillaceae are an intensively studied family of bacteria widely used in fermented food and probiotics, and many are native to the gut and vaginal microbiota of humans and other animals. Various studies have shown that specific Lactobacillaceae species produce metabolites that can inhibit the colonization of fungal and bacterial pathogens, but less is known about how Lactobacillaceae affect individual bacterial species in the endogenous animal microbiota. Here, we show that numerous Lactobacillaceae species inhibit the growth of the Lachnospiraceae family and the S24-7 group, two dominant clades of bacteria within the gut. We demonstrate that inhibitory activity is a property common to homofermentative Lactobacillaceae species, but not to

SUBMITTER: Brownlie EJE 

PROVIDER: S-EPMC8920129 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature