Autologous Reconstruction after Mastectomy for Breast Cancer.

ABSTRACT:

Background

Women undergoing autologous reconstruction (AR) after mastectomy for breast cancer and their surgeons must make decisions regarding timing of the AR and choose among various flap types. We conducted a systematic review to evaluate the comparative benefits and harms of (1) timing of AR relative to chemotherapy and radiation therapy, and (2) various flap types for AR.

Methods

We searched Medline, Embase, Cochrane CENTRAL, CINAHL, and ClinicalTrials.gov for studies, from inception to March 23, 2021, without language restriction. We assessed risk of bias of individual studies and strength of evidence (SoE) of our findings using standard methods.

Results

We screened 15,936 citations. Twelve mostly high risk of bias studies, including three randomized controlled

SUBMITTER: Saldanha IJ 

PROVIDER: S-EPMC8920301 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature