Impact of colchicine on mortality and morbidity in COVID-19: a systematic review.

ABSTRACT:

Introduction

Colchicine, because of its anti-inflammatory and possible anti-viral properties, has been proposed as potential therapeutic option for COVID-19. The role of colchicine to mitigate "cytokine storm" and to decrease the severity and mortality associated with COVID-19 has been evaluated in many studies.

Objective

To evaluate the role of colchicine on morbidity and mortality in COVID-19 patients.

Methods

This systematic review was conducted in accordance with the PRISMA recommendations. The literature search was conducted in 6 medical databases from inception to February 17, 2021 to identify studies evaluating colchicine as a therapeutic agent in COVID-19. All included studies were evaluated for risk of bias (ROB) using the Revised Cochrane ROB tool for random

SUBMITTER: Sanghavi D 

PROVIDER: S-EPMC8920395 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature