Extra-Axial Skeletal Metastasis of Malignant Melanoma: Case Report and Literature Review.

ABSTRACT: The incidence of malignant melanoma is increasing worldwide and is one of the major causes of skin cancer deaths in the United States. Although melanoma has the potential to metastasize to any organ, the incidence of bone metastasis is low (~25%) compared to liver or lung metastasis. However, when a bone is involved, metastasis occurs to the axial skeleton in most cases (80%-90%), and involvement of the appendicular skeleton is relatively rare. We here describe the case of a patient who presented with a pathological fracture due to extra-axial skeletal metastasis of a widespread malignant melanoma.  A 45-year-old female with an unremarkable past medical history presented to the ED with acute left hip pain. X-ray demonstrated left intertrochanteric femur fracture with an abnormal, suspiciou

SUBMITTER: Gullapalli K 

PROVIDER: S-EPMC8920794 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature