MRI grading for the prediction of prostate cancer aggressiveness.

ABSTRACT:

Objectives

T o evaluate the value of multiparametric MRI (mpMRI) for the prediction of prostate cancer (PCA) aggressiveness.

Methods

In this single center cohort study, consecutive patients with histologically confirmed PCA were retrospectively enrolled. Four different ISUP grade groups (1, 2, 3, 4-5) were defined and fifty patients per group were included. Several clinical (age, PSA, PSAD, percentage of PCA infiltration) and mpMRI parameters (ADC value, signal increase on high b-value images, diameter, extraprostatic extension [EPE], cross-zonal growth) were evaluated and correlated within the four groups. Based on combined descriptors, MRI grading groups (mG1-mG3) were defined to predict PCA aggressiveness.

Results

In total, 200 patients (mean age 68 years, median P

SUBMITTER: Boschheidgen M 

PROVIDER: S-EPMC8921105 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature