Pilot study of autologous fecal microbiota transplants in nursing home residents: Feasibility and safety.

ABSTRACT:

Introduction

Antibiotic resistant bacterial infections (ARBIs) are extremely common in nursing home residents. These infections typically occur after a course of antibiotics, which eradicate both pathological and beneficial organisms. The eradication of beneficial organisms likely facilitates subsequent ARBIs. Autologous fecal microbiota transplant (aFMT) has been proposed as a potential treatment to reduce ARBIs in nursing home residents. Our objective was to determine the feasibility and safety of aFMT in a nursing home population.

Methods

Pilot clinical trial. We evaluated feasibility as total number of stool samples collected for aFMT production and safety as the number and relatedness of serious (SAE) and non-serious adverse events (AE).

Results

We screened 468 n

SUBMITTER: Liu CK 

PROVIDER: S-EPMC8921299 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature