Ontology-aware neural network: a general framework for pattern mining from microbiome data.

ABSTRACT: With the rapid accumulation of microbiome data around the world, numerous computational bioinformatics methods have been developed for pattern mining from such paramount microbiome data. Current microbiome data mining methods, such as gene and species mining, rely heavily on sequence comparison. Most of these methods, however, have a clear trade-off, particularly, when it comes to big-data analytical efficiency and accuracy. Microbiome entities are usually organized in ontology structures, and pattern mining methods that have considered ontology structures could offer advantages in mining efficiency and accuracy. Here, we have summarized the ontology-aware neural network (ONN) as a novel framework for microbiome data mining. We have discussed the applications of ONN in multiple contexts, i

SUBMITTER: Zha Y 

PROVIDER: S-EPMC8921649 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature