Development and Validation of a Ferroptosis-Related lncRNAs Prognosis Model in Oral Squamous Cell Carcinoma.

ABSTRACT: Objectives: Ferroptosis is an iron-dependent form of programmed cell death, which affects the prognosis of many cancers. Some long non-coding RNA (lncRNA) can affect the prognosis of cancer by regulating the process of ferroptosis. However, the role of ferroptosis-related lncRNA (frlncRNA) in oral squamous cell carcinoma (OSCC) is not yet clear. Materials and Methods: The data of OSCC patients were downed from The Cancer Genome Atlas (TCGA). After univariate and multivariate Cox regression analysis, the prognosis-related ferroptosis-related lncRNAs were obtained to construct a prognostic model. Calculated the risk score to divide patients into high and low risk groups, and evaluated the predictive ability of the model and the differential expression of immunity in the high an

SUBMITTER: Li T 

PROVIDER: S-EPMC8921664 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature