Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study.

ABSTRACT: Background: Human challenge studies involve the deliberate exposure of healthy volunteers to an infectious micro-organism in a highly controlled and monitored way. They are used to understand infectious diseases and have contributed to the development of vaccines. In early 2020, the UK started exploring the feasibility of establishing a human challenge study with SARS-CoV-2. Given the significant public interest and the complexity of the potential risks and benefits, it is vital that public views are considered in the design and approval of any such study and that investigators and ethics boards remain accountable to the public. Methods: Mixed methods study comprising online surveys conducted with 2,441 UK adults and in-depth virtual focus groups with 57 UK adults during Octo

SUBMITTER: Barker C 

PROVIDER: S-EPMC8921687 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature