Characteristics of patients with systemic sclerosis suffering from a lower limb amputation: Results of a French collaborative study.

ABSTRACT:

Objective

Systemic sclerosis mainly affects the microvascular network. However, macrovascular manifestations have been reported. We aimed to investigate the characteristics of systemic sclerosis patients with an amputation of a lower limb segment.

Methods

We designed a retrospective, case-control, multicentric study on systemic sclerosis patients with amputation of a lower limb segment secondary to critical ischemia via the French Research Group on Systemic Sclerosis. For each case, a control (systemic sclerosis patient without lower limb symptom) was matched with sex, age (±5 years), and cutaneous subset of systemic sclerosis.

Results

In total, 26 systemic sclerosis patients (mean age of 67.2 ± 10.9 years, 20 females, 21 limited cutaneous forms) with a lower limb amp

SUBMITTER: Bertolino J 

PROVIDER: S-EPMC8922619 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature