Mortality and morbidity in scleroderma renal crisis: A systematic literature review.

ABSTRACT:

Objectives

The objective of this study was to systematically review the mortality and morbidity associated with scleroderma renal crisis and to determine temporal trends.

Methods

We searched MEDLINE, Embase and the Cochrane Database of Systematic Reviews from database inception to 10 February 2020. Bibliographies of selected articles were hand-searched for additional references. Data were extracted using a standardized extraction form. Study quality was assessed using the Newcastle-Ottawa scale. Results were analysed qualitatively.

Results

Twenty studies with 14,059 systemic sclerosis subjects, of which 854 had scleroderma renal crisis and 4095 had systemic sclerosis-associated end-stage renal disease, met inclusion criteria. Study quality was generally moderate. Cumu

SUBMITTER: Kim H 

PROVIDER: S-EPMC8922629 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature