Determination of profenofos in seawater and foodstuff samples after its molecularly imprinted polymer pipette-tip micro solid phase extraction optimized by response surface methodology.

ABSTRACT:

Background

In this research, a molecularly imprinted polymer (MIP) was synthesized and employed as a sorbent for pipette-tip micro solid phase extraction of profenofos insecticide in seawater, rice, and fish samples. The instrument employed for quantitation was spectrophotometry.

Results

Various factors affecting the microextraction protocol, including type and volume of the elution solvent, weight of MIP, pH and volume of sample solution, and number of cycles of loading and desorption were considered and optimized using one-factor-at-a-time, central composite design and Box-Behnken design. Factors optimized at: pH 4.0, amount of sorbent 2.5 mg, volume of methanol:acetic (9:1) acid as eluent 250 µL, both the number of extraction and elution cycles 5, and volume of sample 8.0

SUBMITTER: Tamandani M 

PROVIDER: S-EPMC8922791 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature