IRIS: Infection with RespIratory Syncytial Virus in infants-a prospective observational cohort study.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infection in infants. Globally, RSV is responsible for approximately 3.2 million hospital admissions and about 60,000 in-hospital deaths per year.

Methods

Infection with RespIratory Syncytial Virus (IRIS) is an observational, multi-centre study enrolling infants with severe RSV infection and healthy controls. Inclusion criteria are age between 0 and 36 months and hospitalisation due to RSV infection at three German sites. Exclusion criteria are premature birth, congenital or acquired bronchopulmonary or cardiac diseases, and immunodeficiency. Healthy control probands are enrolled via recruitment of patients undergoing routine surgical procedures. Blood and respiratory speci

SUBMITTER: Wetzke M 

PROVIDER: S-EPMC8922907 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature