Short Stature: Understanding the Stature of Ethnicity in Height Determination.

ABSTRACT: Height is a polygenic trait with a high degree of heritability. Most (95%) children with short stature (defined as height below the third percentile) and poor growth (growth velocity <5 cm/year) do not have an endocrine disorder. The genetic basis for stature potential has been evaluated in recent years and is increasingly being recognized as a major basis for variation in height between different ethnic populations. Numerous genome-wide association studies have identified hundreds of loci linked to human growth. Apart from the genetic factors, various environmental, nutritional, hormonal, and socioeconomic factors also influence the height, and stature of individuals varies between different geographical locations and ethnic groups. Ethnically different populations might respond different

SUBMITTER: Mittal M 

PROVIDER: S-EPMC8923322 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature