Failure properties of ascending thoracic aortic aneurysms with dysfunctional tricuspid aortic valves.

ABSTRACT:

Objectives

Ascending thoracic aortic aneurysms (ATAAs) often coexist with dysfunctional tricuspid aortic valves (TAVs). How valvular pathology relates to the aortic wall mechanical properties requires detailed examination.

Methods

Intact-wall and layer-specific mechanical properties from 40 and 21 patients with TAV-ATAAs, respectively, were studied using uniaxial tensile testing, longitudinally and circumferentially. Failure stress (tensile strength), failure stretch (extensibility) and peak elastic modulus (stiffness) measurements, along with histological assays of thickness and elastin/collagen contents, were compared among patients with no valvular pathology (NVP), aortic stenosis (AS) or aortic insufficiency (AI).

Results

Intact-wall stiffness longitudinally and m

SUBMITTER: Sokolis DP 

PROVIDER: S-EPMC8923381 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature