Metabolomics and Microbiomics: New Potential Strategies in Chronic Pain Syndrome.

ABSTRACT: Chronic pain affects almost 20% of the European adult population and it significantly reduces patients' quality of life. Chronic pain is considered a multidimensional experience determined by the interaction of several genetic and environmental factors. The effect of specific genetic contributions is often unclear, and the interpretation of the results from studies focused on genetic influences on pain has been complicated by the existence of multiple pain phenotypes. A step forward from genetics could be given by the application of metabolomics and microbiomics tools. Metabolomics is a powerful approach for hypothesis generation in biology, and it aims to analyze low molecular weight compounds, either metabolic intermediates or metabolic end-products, resulting from human or microbial met

SUBMITTER: Piras C 

PROVIDER: S-EPMC8923834 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature