Performance characteristics of ¹⁸F-fluciclovine positron emission tomography/computed tomography prior to retroperitoneal lymph node dissection.

ABSTRACT:

Introduction

We aimed to determine whether anti-1-amino-3-¹⁸F-fluorocyclobutane-1-carboxylic acid (¹⁸F-fluciclovine) positron emission tomography/computed tomography (PET/CT) can accurately detect residual non-seminomatous germ cell tumor (NSGCT) prior to retroperitoneal lymph node dissection (RPLND). There is no reliable way to differentiate between fibrosis/necrosis, teratoma, and viable germ cell tumor in patients receiving post-chemotherapy RPLND. Functional imaging, including ¹⁸F-fludeoxyglucose (18F-FDG) PET/CT, has been disappointing. Due to the need for better imaging modalities, our prospective, pilot study aims to investigate the accuracy of ¹⁸F-fluciclovine PET/CT in detecting residual tumor prior to RPLND.

Methods

From

SUBMITTER: Woldu SL 

PROVIDER: S-EPMC8923889 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature