Effect of five nights of sleep extension on peripheral vascular function: a randomized crossover investigation into long sleep duration.

ABSTRACT: Long sleep duration, defined as ≥9 h, is associated with increased cardiovascular mortality. We sought to determine the effect of sleep extension on peripheral vascular health. Twelve middle-aged adults were randomly assigned to spend five nights with 8 h (control) or 10+ hours time in bed (TIB) in a crossover fashion. Sleep was assessed using wrist actigraphy. Peak reactive hyperemia in the forearm was measured using venous-occlusion plethysmography as an index of microvascular vasodilation. Nighttime and morning blood pressure was recorded along with pulse wave velocity (arterial stiffness). Average sleep duration was 7.1 ± 0.3 and 9.3 ± 0.3 h for 8 and 10+ hours TIB (P < 0.001), respectfully. On average, sleep was extended by 127 ± 29 min with nine participants reaching average sleep du

SUBMITTER: Gonzales JU 

PROVIDER: S-EPMC8923941 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature