Maternal occupational physical activity and risk for orofacial clefts.

ABSTRACT:

Objectives

To perform a case-control study of maternal occupational physical activity and risk for orofacial clefts in Texas during 1999-2009.

Methods

We used logistic regression to assess 14 measures of physical activity estimated from a job exposure matrix, using the maternal occupation reported on the birth certificate, among 887 children with cleft lip with or without cleft palate (CLP), 436 children with cleft palate only (CP), and 1932 controls.

Results

After adjusting for several potential confounders, seven measures of physical activity (as a categorical and/or continuous variable) were significantly associated with CLP, CP, or both. Positive associations were seen for keeping balance, kneeling, standing, and walking/running (odds ratio 95% confidence interval

SUBMITTER: Agopian AJ 

PROVIDER: S-EPMC8924980 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature