Day-To-Day Home Blood Pressure Variability and All-Cause Mortality in a Memory Clinic Population.

ABSTRACT:

Background

High day-to-day blood pressure variability (BPV) has been associated with an increased risk for cognitive decline and mortality in the general population. Whether BPV is associated with increased all-cause mortality in older people with cognitive impairment is unknown.

Objective

To investigate the association between day-to-day home BPV and all-cause mortality in older patients attending a memory clinic.

Methods

We included 279 patients attending a memory clinic, who measured home blood pressure (BP) for 7 consecutive days in the morning and evening. Within-subject BPV was defined as the variation independent of the mean (VIM). Time-to-death was verified through the Dutch population registry. Cox proportional hazard regression was used. Separate analyses we

SUBMITTER: Haverkamp RA 

PROVIDER: S-EPMC8925104 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature