Positive fecal immunochemical test results are associated with non-colorectal cancer mortality.

ABSTRACT:

Background/aims

Studies have reported an association between fecal occult blood and increased all-cause, non-colorectal cancer (CRC) as well as CRC mortality. This study aimed to determine whether positive fecal immunochemistry test (FIT) results are associated with death from various causes in the South Korean population.

Methods

Using the Korean National Cancer Screening Program database, we collected data on patients who underwent FIT between 2009 and 2011.

Results

Of the 5,932,544 participants, 380,789 (6.4%) had positive FIT results. FIT-positive participants had a higher mortality rate than FIT-negative participants from CRC (1.33 and 0.21 per 1,000 person-years, p < 0.001, respectively) and non-CRC causes (10.40 and 7.50 per 1,000 person-years, p < 0.001, respe

SUBMITTER: Jung YS 

PROVIDER: S-EPMC8925959 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature