High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers.

ABSTRACT:

Background

COVID-19 pandemic has a devastating impact on the economies and health care system of sub-Saharan Africa. Healthcare workers (HWs), the main actors of the health system, are at higher risk because of their occupation. Serology-based estimates of SARS-CoV-2 infection among HWs represent a measure of HWs' exposure to the virus and could be used as a guide to the prevalence of SARS-CoV-2 in the community and valuable in combating COVID-19. This information is currently lacking in Ethiopia and other African countries. This study aimed to develop an in-house antibody testing assay, assess the prevalence of SARS-CoV-2 antibodies among Ethiopian high-risk frontline HWs.

Methods

We developed and validated an in-house Enzyme-Linked Immunosorbent Assay (ELISA) for specific

SUBMITTER: Gelanew T 

PROVIDER: S-EPMC8926102 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature