Helicity-driven chiral self-sorting supramolecular polymerization with Ag⁺: right- and left-helical aggregates.

ABSTRACT: The study of chiral self-sorting is extremely important for understanding biological systems and for developing applications for the biomedical field. In this study, we attempted unprecedented chiral self-sorting supramolecular polymerization accompanying helical inversion with Ag⁺ in one enantiomeric component. Bola-type terpyridine-based ligands (R-L¹ and S-L¹) comprising R- or S-alanine analogs were synthesized. First, R-L¹ dissolved in DMSO/H₂O (1 : 1, v/v) forms right-handed helical fibers (aggregate I) via supramolecular polymerization. However, after the addition of AgNO₃ (0.2-1.1 equiv.) to the R-L¹ ligand, in particular, it was found that aggregate II with

SUBMITTER: Ok M 

PROVIDER: S-EPMC8926169 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature