Assessment of a cellular host response test to risk-stratify suspected COVID-19 patients in the Emergency Department setting.

ABSTRACT:

Objective

Assess the IntelliSep Index (ISI) for risk stratification of patients presenting to the Emergency Department (ED) with respiratory symptoms suspected of COVID-19 during the pandemic.

Methods

An observational single-center study of prospective cohort of patients presenting to the ED during the early COVID-19 pandemic with respiratory symptoms and a CBC drawn within 4.5 hours of initial vital signs. A sample of this blood was aliquoted for performance of the ISI, and patients were followed for clinical outcomes. The study required no patient-centered activity beyond standard of care and treating clinicians were unaware of study enrollment and ISI test results.

Main findings

282 patients were included. The ISI ranges 0.1 to 10.0, with three interpretation bands

SUBMITTER: O'Neal HR 

PROVIDER: S-EPMC8926179 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature