New scoring systems for predicting advanced proximal neoplasia in asymptomatic adults with or without knowing distal colorectal findings: a prospective, cross-sectional study.

ABSTRACT:

Background

Models estimating risk for advanced proximal colorectal neoplasia (APN) may be used to select colorectal cancer (CRC) screening test, either prior to knowing distal colorectal findings or afterward. Current models have only fair discrimination and nearly all require knowing distal findings.

Objective

Derive and test risk prediction models for APN with and without distal findings.

Setting

Selected endoscopy centers within central Indiana, USA.

Participants

Average-risk persons undergoing first-time screening colonoscopy.

Interventions

Demographics, personal and family medical history, lifestyle factors and physical measures were linked to the most advanced finding in proximal and distal colorectal segments. For both models, logistic regression

SUBMITTER: Imperiale TF 

PROVIDER: S-EPMC8926932 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature