Protein tau concentration in blood increases after SCUBA diving: an observational study.

ABSTRACT:

Purpose

It is speculated that diving might be harmful to the nervous system. The aim of this study was to determine if established markers of neuronal injury were increased in the blood after diving.

Methods

Thirty-two divers performed two identical dives, 48 h apart, in a water-filled hyperbaric chamber pressurized to an equivalent of 42 m of sea water for 10 min. After one of the two dives, normobaric oxygen was breathed for 30 min, with air breathed after the other. Blood samples were obtained before and at 30-45 and 120 min after diving. Concentrations of glial fibrillary acidic, neurofilament light, and tau proteins were measured using single molecule array technology. Doppler ultrasound was used to detect venous gas emboli.

Results

Tau was significantly increase

SUBMITTER: Rosen A 

PROVIDER: S-EPMC8926952 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature