Frailty as a predictor of mortality in COVID-19 patients receiving CPAP for respiratory insufficiency.

ABSTRACT:

Objective

Exploring the association between frailty and mortality in a cohort of patients with COVID-19 respiratory insufficiency treated with continuous positive airway pressure.

Methods

Frailty was measured using a Frailty Index (FI) created by using the baseline assessment data on comorbidities and body mass index and baseline blood test results (including pH, lactate dehydrogenase, renal and liver function, inflammatory indexes and anemia). FI > 0.25 identified frail individuals.

Results

Among the 159 included individuals (81% men, median age of 68) frailty was detected in 69% of the patients (median FI score 0.3 ± 0.08). Frailty was associated to an increased mortality (adjusted HR 1.99, 95% CI 1.02-3.88, p = 0.04).

Conclusions

Frailty is highly prevalent

SUBMITTER: Damanti S 

PROVIDER: S-EPMC8927756 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature