Neural synchronization analysis of electroencephalography coherence in patients with Parkinson's disease-related mild cognitive impairment.

ABSTRACT:

Introduction

The underlying pathophysiology of slight cognitive dysfunction in Parkinson's disease-related mild cognitive impairment (PD-MCI) is yet to be elucidated. Our study aimed to evaluate the association between cognitive function and brain functional connectivity (FC) in patients with PD-MCI.

Methods

Twenty patients with sporadic PD-MCI were evaluated for FC in the brain network. Further, electroencephalography (EEG) coherence analysis in the whole-brain and quantified regional coherence using phase coupling were performed for each frequency, and motor and cognitive function were assessed in the whole-brain.

Results

The degree of cognitive impairment was related to a decrease in the coherence in the alpha ranges. The regional coherence in the left frontal-left

SUBMITTER: Mano T 

PROVIDER: S-EPMC8928128 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature