The Impact of the Antibiotic Fosfomycin on Wastewater Communities Measured by Flow Cytometry.

ABSTRACT: Fosfomycin is a re-emergent antibiotic known to be effective against severe bacterial infections even when other antibiotics fail. To avoid overuse and thus the risk of new antibiotic resistance, the European Commission has recommended the intravenous use of fosfomycin only when other antibiotic treatments fail. A release of fosfomycin into the environment via wastewater from not only municipalities but also already from the producing pharmaceutical industry can seriously undermine a sustaining therapeutic value. We showed in long-term continuous-mode bioreactor cultivation and by using microbial community flow cytometry, microbial community ecology tools, and cell sorting that the micro-pollutant altered the bacterial wastewater community (WWC) composition within only a few generat

SUBMITTER: Li S 

PROVIDER: S-EPMC8928225 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature