A Comparative Study between Spanish and British SARS-CoV-2 Variants.

ABSTRACT: The study of the interaction between the SARS-CoV-2 spike protein and the angiotensin-converting enzyme 2 (ACE2) receptor is key to understanding binding affinity and stability. In the present report, we sought to investigate the differences between two already sequenced genome variants (Spanish and British) of SARS-CoV-2. Methods: In silico model evaluating the homology, identity and similarity in the genome sequence and the structure and alignment of the predictive spike by computational docking methods. Results: The identity results between the Spanish and British variants of the Spike protein were 28.67%. This close correspondence in the results between the Spanish and British SARS-CoV-2 variants shows that they are very similar (99.99%). The alignment obtained results in

SUBMITTER: Jimenez Ruiz JA 

PROVIDER: S-EPMC8929045 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature