Health-related quality of life in cancer immunotherapy: a systematic perspective, using causal loop diagrams.

ABSTRACT:

Purpose

System science offers a unique set of tools, including causal loop diagrams (CLDs), for stakeholders to better grasp the complexity of factors surrounding quality of life. Because the health-related quality of life (HRQoL) of cancer immunotherapy patients exists within an intricate system affected by and affecting many factors across multiple dimensions, the development of a systems-level model can provide a powerful framework to aid the understanding of this complexity. We developed a CLD for HRQoL of cancer immunotherapy patients.

Methods

We first applied a literature-based approach to construct a CLD for patients following immunotherapy. We then iteratively reviewed and enhanced the CLD through interviews with subject matter experts.

Results

Based on the re

SUBMITTER: Beaulieu E 

PROVIDER: S-EPMC8929267 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature