Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar.

ABSTRACT:

Background

Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and the emergence of the omicron (or B.1.1.529) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to expedited efforts to scale up booster vaccination. Protection conferred by booster doses of the BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) vaccines in Qatar, as compared with protection conferred by the two-dose primary series, is unclear.

Methods

We conducted two matched retrospective cohort studies to assess the effectiveness of booster vaccination, as compared with that of a two-dose primary series alone, against symptomatic SARS-CoV-2 infection and Covid-19-related hospitalization and death during a large wave of omicron infections from December 1

SUBMITTER: Abu-Raddad LJ 

PROVIDER: S-EPMC8929389 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature