Verbal Training Induces Enhanced Functional Connectivity in Japanese Healthy Elderly Population.

ABSTRACT: This study employs fMRI to examine the neural substrates of response to cognitive training in healthy old adults. Twenty Japanese healthy elders participated in a 4-week program and practiced a verbal articulation task on a daily basis. Functional connectivity analysis revealed that in comparison to age- and education-matched controls, elders who received the cognitive training demonstrated increased connectivity in the frontotemporal regions related with language and memory functions and showed significant correlations between the behavioral change in a linguistic task and connectivity in regions for goal-oriented persistence and lexical processing. The increased hippocampal connectivity was consistent with previous research showing efficacious memory improvement and change in hippocampal

SUBMITTER: Yang FG 

PROVIDER: S-EPMC8930077 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature