Ontology highlight
ABSTRACT:
SUBMITTER: Mikhael JG
PROVIDER: S-EPMC8930519 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Mikhael John G JG Kim HyungGoo R HR Uchida Naoshige N Gershman Samuel J SJ
Current biology : CB 20220202 5
Reinforcement learning models of the basal ganglia map the phasic dopamine signal to reward prediction errors (RPEs). Conventional models assert that, when a stimulus predicts a reward with fixed delay, dopamine activity during the delay should converge to baseline through learning. However, recent studies have found that dopamine ramps up before reward in certain conditions even after learning, thus challenging the conventional models. In this work, we show that sensory feedback causes an unbia ...[more]