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Molecular characterization of multidrug resistance in Streptococcus mitis.

ABSTRACT: Antimicrobial resistance was characterized for 14 strains of Streptococcus mitis. HinfI restriction fragment length mapping of gyrA PCR amplicons from three ciprofloxacin-resistant isolates correlated with mutations associated with such resistance in other organisms. By using PCR, seven erythromycin-resistant strains were found to possess either the mef or ermB gene. Hybridization revealed tet(M) in seven tetracycline-resistant isolates.

SUBMITTER: Poutanen SM 

PROVIDER: S-EPMC89309 | biostudies-literature | 1999 Jun

REPOSITORIES: biostudies-literature

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Molecular characterization of multidrug resistance in Streptococcus mitis.

Poutanen S M SM   de Azavedo J J   Willey B M BM   Low D E DE   MacDonald K S KS  

Antimicrobial agents and chemotherapy 19990601 6

Antimicrobial resistance was characterized for 14 strains of Streptococcus mitis. HinfI restriction fragment length mapping of gyrA PCR amplicons from three ciprofloxacin-resistant isolates correlated with mutations associated with such resistance in other organisms. By using PCR, seven erythromycin-resistant strains were found to possess either the mef or ermB gene. Hybridization revealed tet(M) in seven tetracycline-resistant isolates. ...[more]

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