Evaluation of Tracheal Stenosis in Rabbits Using Multispectral Optoacoustic Tomography.

ABSTRACT: Objective: Photoacoustic tomography (PAT) and multispectral optoacoustic tomography (MSOT) are evolving technologies that are capable of delivering real-time, high-resolution images of tissues. The purpose of this study was to evaluate the feasibility of using PAT and MSOT for detecting histology in a rabbit tracheal stenosis model.
 Method: A total of 12 rabbits (9 stenosis and three control) were randomly divided into four groups (A, B, C and D). Each group consisted of three rabbits, which were staged at the first, fourth, and eighth weeks of stenosis progression, respectively. PAT/MSOT images and corresponding histology from these experimental animals were compared, for analyzing the morphologic features and quantitative tracheal measurements in different tracheal stenosi

SUBMITTER: Wen Y 

PROVIDER: S-EPMC8931196 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature