Risk of Colorectal Cancer Associated With Lifetime Excess Weight.

ABSTRACT:

Importance

Excess weight is associated with increased cancer risk, but the risk may have been underestimated, as previous studies did not consider cumulative lifetime exposure.

Objective

To assess the association of cumulative lifetime excess weight with risk of colorectal cancer (CRC).

Design, setting, and participants

In a population-based case-control study conducted since 2003 in Germany, height and self-reported weight documented in 10-year increments starting at age 20 years up to the current age were obtained from 5635 individuals with CRC and 4515 persons serving as controls. Body mass index (BMI), calculated as weight in kilograms divided by height in meters squared, was calculated for each year of age from age 20 years to the current age by linear interpolat

SUBMITTER: Li X 

PROVIDER: S-EPMC8931669 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature