Portulaca oleracea Polysaccharides Modulate Intestinal Microflora in Aged Rats in vitro.

ABSTRACT: To explore the effect of Portulaca oleracea polysaccharides (POP) in regulating intestinal microflora in aged rats in vitro, its intestinal microbial composition was analyzed by 16 S rDNA high-throughput sequencing, and the level of short-chain fatty acids in fermentation broth was determined by LC-MS. POP significantly upregulated the relative abundance of Lactobacillus, Eggerthella, and Paraprevotella and significantly downregulated Escherichia_Shigella, Bacteroides, and Eubacterium nodatum groups. The pH value and ammonia nitrogen level decreased significantly in the POP-treated group, resulting in a more short-chain fatty acid consumption which changed the acid-base environment of the fermentation broth. In conclusion, POP is bene

SUBMITTER: Fu Q 

PROVIDER: S-EPMC8931684 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature