Plasma Concentration of the Lipid Peroxidation (LP) Biomarker 4-Ηydroxynonenal (4-HNE) in Benign and Cancer Patients.

ABSTRACT:

Background/aim

The present study investigated the plasma concentration of the lipid peroxidation (LP) biomarker 4-hydroxynonenal (4-HNE) in benign and cancer patients having the rectus sheath block (RSB) analgesia after midline laparotomy. Plasma concentrations of catalase (CAT) and malondialdehyde (MDA) were used as a reference.

Patients and methods

This study assessed three LP biomarkers; CAT, MDA and 4-HNE and compared the plasma levels to the patient satisfaction 24 h postoperatively (SFS₂₄; 0=fully unsatisfied; 10=fully satisfied); the overall pain at rest (NRS_r) and when pressing the wound at 20 Newton force (NRS_p) were surveyed and filed on a 11-point numeric rating scale at 24 h following surgery (NRS; 0=no pain; 10=worst pain). There

SUBMITTER: Eskelinen M 

PROVIDER: S-EPMC8931927 | biostudies-literature | 2022 Mar-Apr

REPOSITORIES: biostudies-literature