Validation of an MRI-only planning workflow for definitive pelvic radiotherapy.

ABSTRACT:

Purpose

Previous work on Magnetic Resonance Imaging (MRI) only planning has been applied to limited treatment regions with a focus on male anatomy. This research aimed to validate the use of a hybrid multi-atlas synthetic computed tomography (sCT) generation technique from a MRI, using a female and male atlas, for MRI only radiation therapy treatment planning of rectum, anal canal, cervix and endometrial malignancies.

Patients and methods

Forty patients receiving radiation treatment for a range of pelvic malignancies, were separated into male (n = 20) and female (n = 20) cohorts for the creation of gender specific atlases. A multi-atlas local weighted voting method was used to generate a sCT from a T1-weighted VIBE DIXON MRI sequence. The original treatment plans were copied

SUBMITTER: O'Connor LM 

PROVIDER: S-EPMC8932060 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature