Home Aerobic Training for Cerebellar Degenerative Diseases: a Randomized Controlled Trial.

ABSTRACT: Balance training has shown some benefits in cerebellar ataxia whereas the effects of aerobic training are relatively unknown. To determine whether a phase III trial comparing home aerobic to balance training in ambulatory patients with cerebellar ataxia is warranted, we conducted a single-center, assessor-blinded, randomized controlled trial. Nineteen subjects were randomized to aerobic training and 17 subjects to balance training. The primary outcome was improvement in ataxia as measured by the Scale for the Assessment and Rating of Ataxia (SARA). Secondary outcomes included safety, training adherence, and balance improvements. There were no differences between groups at baseline. Thirty-one participants completed the trial, and there were no training-related serious adverse events. Compl

SUBMITTER: Barbuto S 

PROVIDER: S-EPMC8932090 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature