Incidence of impaired kidney function among people with HIV: a systematic review and meta-analysis.

ABSTRACT:

Background

In the era of combination antiretroviral therapy (ART), the incidence, manifestations and severity of kidney diseases have dramatically changed in people living with HIV (PLWH). Little is known about the incidence of impaired kidney function (IKF) measured by serum creatine-based estimated glomerular filtration rate (eGFR) in PLWH.

Methods

In this systematic review and meta-analysis, we searched PubMed, Ovid, Medline, Embase and Web of Science for studies published before May 7th, 2021, with estimates of incidence of IKF among PLWH. We independently reviewed each study for quality by using the Newcastle-Ottawa scale. The incidence and 95% confidence intervals (CIs) were calculated using random-effects model.

Results

Sixty out of 3797 identifiable studies we

SUBMITTER: Shi R 

PROVIDER: S-EPMC8932163 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature